Volume 4, Number 2 (Autumn & Winter 2010)                   IJPBS 2010, 4(2): 56-57 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Fatemi S H, D Folsom T. Fragile X Mental Retardation Protein is Reduced in Cerebella of Subjects with Autism. IJPBS. 2010; 4 (2) :56-57
URL: http://ijpbs.mazums.ac.ir/article-1-81-en.html

Abstract:   (3313 Views)
Autism and fragile X syndrome have multiple behavioral phenotypes in common, however there has been little research into the potential role of fragile X mental retardation protein (FMRP) in autism. We sought to measure protein levels of FMRP in the lateral cerebella of subjects with autism and matched controls. We found significantly reduced levels of FMRP (p<0.0063) in subjects with autism. The loss of FMRP expression in subjects with autism may help explain behavioral deficits, presence of seizure, and reduction in GABA receptors in subjects with autism.
Full-Text [PDF 205 kb]   (975 Downloads)    
Type of Study: Research | Subject: Psychiatry
Received: 2012/05/27 | Accepted: 2014/01/6 | Published: 2014/01/6

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Iranian Journal of Psychiatry and Behavioral Sciences

Designed & Developed by : Yektaweb